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Two by Two, two by two, 2×2 or 2by2 may refer to:

Arts, entertainment and media

Film and television

• 2×2 (TV channel), a TV channel in Russia
• Two by Two, or Ooops! Noah Is Gone..., a 2015 animated film
• "Two By Two", a Rugrats TV episode

Music and musicals

• Two by Two (musical), a 1970 Broadway show with music by Richard Rodgers

Albums

• Two by Two (album), by Blue Zoo, 1983
• 2x2 (album), a boxed set of albums by Milli Vanilli, 1989
• 2 X 2, a 1997 album by Gigi
• II x II, a 1970 album by The Cowsills

Songs

• "Two by Two", from the musical The Book of Mormon
• "Two By Two", a song by Quasi from the 1999 album Field Studies
• "2 X 2", a song by Bob Dylan from the 1990 album Under the Red Sky
• Two by Two, a 1988 song by Cristiana Cucchi

Other uses

• 2x2, a two-wheeled two-wheel drive vehicle
• 2by2, an American lottery game
• 2x2 Project, a public health journalism initiative
• Two-by-two matrix, a square matrix of order 2

See also

• Two (disambiguation)
• 2+2 (disambiguation)
• Two two (disambiguation)
• Pocket Cube, a puzzle device also known as a 2×2×2 Rubik's Cube
• Two by Twos, a Christian based religious movement/organization

• Disambiguation pages