Misplaced Pages

In enzymology, a 4-formylbenzenesulfonate dehydrogenase (EC 1.2.1.62) is an enzyme that catalyzes the chemical reaction

4-formylbenzenesulfonate + NAD + H₂O ${\displaystyle \rightleftharpoons }$ 4-sulfobenzoate + NADH + 2 H

The 3 substrates of this enzyme are 4-formylbenzenesulfonate, NAD, and H₂O, whereas its 3 products are 4-sulfobenzoate, NADH, and H.

This enzyme belongs to the family of oxidoreductases, specifically those acting on the aldehyde or oxo group of donor with NAD+ or NADP+ as acceptor. The systematic name of this enzyme class is 4-formylbenzenesulfonate:NAD+ oxidoreductase. This enzyme participates in 2,4-dichlorobenzoate degradation.

References

• Cook AM; Saller, E; Schläfli Oppenberg, HR; Kroneck, PM; Leisinger, T; Cook, AM (1 September 1996). "Degradative pathways for p-toluenecarboxylate and p-toluenesulfonate and their multicomponent oxygenases in Comamonas testosteroni strains PSB-4 and T-2". Microbiology. 142 (9): 2419–27. doi:10.1099/00221287-142-9-2419. PMID 8828208.
• Junker F, Kiewitz R, Cook AM (February 1997). "Characterization of the p-toluenesulfonate operon tsaMBCD and tsaR in Comamonas testosteroni T-2". J. Bacteriol. 179 (3): 919–27. doi:10.1128/jb.179.3.919-927.1997. PMC 178777. PMID 9006050.

• Biology

• v
• t
• e

• EC 1.2.1
• NADH-dependent enzymes
• Enzymes of unknown structure
• EC 1.2 stubs