AF1 or AF-1 may refer to:
- Air Force One, the air traffic callsign for the plane (if operated by the Air Force) that the President of the United States is aboard
- Arena Football League, a new Arena football league in the US that was originally planned to be named Arena Football 1
- USS Bridge (AF-1), the lead ship of her class of stores ships for the US Navy
- Air Force 1 (shoe), a shoe produced by Nike, Inc.
- Methyl fluoroacetate
See also
- Air Force One (disambiguation)
- First Air Force (1 AF), USAF numbered air force
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