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Names | |||
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Preferred IUPAC name 1,2-Di(propan-2-ylidene)hydrazine | |||
Systematic IUPAC name Acetone azine | |||
Other names
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Identifiers | |||
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3D model (JSmol) | |||
Beilstein Reference | 4-01-00-03207 | ||
ChemSpider | |||
ECHA InfoCard | 100.010.009 | ||
EC Number |
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PubChem CID | |||
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CompTox Dashboard (EPA) | |||
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Properties | |||
Chemical formula | C6H12N2 | ||
Molar mass | 112.176 g·mol | ||
Appearance | Pale-yellow liquid | ||
Density | 0.842 g cm | ||
Melting point | −125 °C (−193 °F; 148 K) | ||
Boiling point | 133 °C (271 °F; 406 K) | ||
Refractive index (nD) | 1.454 | ||
Hazards | |||
GHS labelling: | |||
Pictograms | |||
Signal word | Danger | ||
Hazard statements | H226, H302, H311, H315, H319, H335, H350 | ||
Precautionary statements | P201, P261, P280, P305+P351+P338, P308+P313 | ||
NFPA 704 (fire diamond) | 3 2 0 | ||
Flash point | 31 °C (88 °F; 304 K) | ||
Related compounds | |||
Related compounds | Hydrazine | ||
Except where otherwise noted, data are given for materials in their standard state (at 25 °C , 100 kPa). Infobox references |
Acetone azine is the simplest ketazine. It is an intermediate in some hydrazine manufacturing processes.
Synthesis
See also: Peroxide processAcetone azine can be prepared from acetone and hydrazine:
- 2 (CH3)2CO + N2H4 → 2 H2O + 2
It can also be produced from acetone (2 eq.), ammonia (2 eq.) and hydrogen peroxide (1 eq.). The first step is the formation of acetone imine, Me2C=NH; this is then oxidized by hydrogen peroxide through a complex mechanism to give 3,3-dimethyloxaziridine, which reacts with a further molecule of ammonia to produce acetone hydrazone. The hydrazone then condenses with a further molecule of acetone to produce the azine. The acetone azine product is distilled out of the reaction mixture as a 1:6 azeotrope with water.
Reactions
Acetone azine can be used to prepare acetone hydrazone and 2-diazopropane [fr].
Hydrazine can be produced through acid-catalysed hydrolysis of acetone azine:
- 2 H2O + 2 → 2 (CH3)2CO + N2H4
References
- "Acetone azine MSDS (Santa Cruz Biotechnology)" (PDF).
- "Acetone azine MSDS (Sigma Aldrich)".
- ^ Day, A. C.; Whiting, M. C. (1970). "Acetone Hydrazone". Organic Syntheses: 3; Collected Volumes, vol. 6, 1988, p. 10.
- US 3972878, Schirmann, Jean-Pierre; Combroux, Jean & Delavarenne, Serge Yvon, "Method for preparing azines and hydrazones", issued 1976-08-03, assigned to Produits Chimiques Ugine Kuhlmann .US 3978049, Schirmann, Jean-Pierre; Tellier, Pierre & Mathais, Henri et al., "Process for the preparation of hydrazine compounds", issued 1976-08-31, assigned to Produits Chimiques Ugine Kuhlmann
- US 4724133, Schirmann, Jean-Pierre; Combroux, Jean & Delavarenne, Serge Y., "Preparation of a concentrated aqueous solution of hydrazine hydrate", issued 1988-02-09, assigned to Atochem
- Andrews, S. D.; Day, A. C.; Raymond, P.; Whiting, M. C. (1970). "2-Diazopropane". Organic Syntheses: 27; Collected Volumes, vol. 6, 1988, p. 392.
- Gilbert, E. C. (1929), "Studies on Hydrazine. The Hydrolysis of Dimethylketazine and the Equilibrium between Hydrazine and Acetone", J. Am. Chem. Soc., 51 (11): 3394–3409, doi:10.1021/ja01386a032.