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Acetylenecarboxylate hydratase

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Class of enzymes
acetylenecarboxylate hydratase producing 3-oxopropanoate
Identifiers
EC no.4.2.1.27
CAS no.9024-26-4
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MetaCycmetabolic pathway
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The enzyme acetylenecarboxylate hydratase (EC 4.2.1.27) catalyzes the chemical reaction

3-oxopropanoate {\displaystyle \rightleftharpoons } propynoate + H2O

This enzyme belongs to the family of lyases, specifically the hydro-lyases, which cleave carbon-oxygen bonds. The systematic name of this enzyme class is 3-oxopropanoate hydro-lyase (propynoate-forming). Other names in common use include acetylenemonocarboxylate hydratase, alkynoate hydratase, acetylenemonocarboxylate hydrase, acetylenemonocarboxylic acid hydrase, malonate-semialdehyde dehydratase, and 3-oxopropanoate hydro-lyase. This enzyme participates in 3 metabolic pathways: beta-alanine metabolism, propanoate metabolism, and butanoate metabolism.

References

  • Probst C, Grotz M, Krettek C, Pape HC (2005). "Impact of hypothermia on the immunologic response after trauma and elective surgery". Surg. Technol. Int. 14: 41–50. PMID 16525953.
  • YAMADA EW, JAKOBY WB (1959). "Enzymatic utilization of acetylenic compounds. II Acetylenemonocarboxylic acid hydrase". J. Biol. Chem. 234 (4): 941–5. PMID 13654296.
Carbon–oxygen lyases (EC 4.2) (primarily dehydratases)
4.2.1: Hydro-Lyases
4.2.2: Acting on polysaccharides
4.2.3: Acting on phosphates
4.2.99: Other
Enzymes
Activity
Regulation
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Kinetics
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