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ARMC12
Identifiers
Aliases	ARMC12, C6orf81, armadillo repeat containing 12
External IDs	MGI: 1914895; HomoloGene: 12168; GeneCards: ARMC12; OMA:ARMC12 - orthologs
Gene location (Human) Chr. Chromosome 6 (human) Band 6p21.31 Start 35,737,032 bp End 35,749,079 bp
Gene location (Mouse) Chr. Chromosome 17 (mouse) Band 17|17 A3.3 Start 28,749,780 bp End 28,758,084 bp
RNA expression pattern Bgee Human Mouse (ortholog) Top expressed in right testis left testis testicle anterior pituitary sperm right lobe of liver left uterine tube left ovary right ovary right adrenal gland Top expressed in seminiferous tubule spermatid spermatocyte granulocyte morula embryo muscle of thigh secondary oocyte yolk sac zygote More reference expression data BioGPS n/a
Orthologs Species Human Mouse Entrez 221481 67645 Ensembl ENSG00000157343 ENSMUSG00000024223 UniProt Q5T9G4 Q80X86 RefSeq (mRNA) NM_001286574 NM_001286576 NM_145028 NM_026290 RefSeq (protein) NP_001273503 NP_001273505 NP_659465 NP_080566 Location (UCSC) Chr 6: 35.74 – 35.75 Mb Chr 17: 28.75 – 28.76 Mb PubMed search
Wikidata
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Armadillo repeat containing 12 is a protein that in humans is encoded by the ARMC12 gene that plays a crucial role in tumor progression. It is associated with the development of neuroblastoma (NB) as it encourages the growth and aggressiveness of NB cell lines.

References

1. ^ GRCh38: Ensembl release 89: ENSG00000157343 – Ensembl, May 2017
2. ^ GRCm38: Ensembl release 89: ENSMUSG00000024223 – Ensembl, May 2017
3. "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
4. "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
5. "Entrez Gene: Armadillo repeat containing 12". Retrieved 2017-12-22.
6. Li D, Song H, Mei H, Fang E, Wang X, Yang F, Li H, Chen Y, Huang K, Zheng L, Tong Q (July 2018). "Armadillo repeat containing 12 promotes neuroblastoma progression through interaction with retinoblastoma binding protein 4". Nature Communications. 9 (1): 2829. Bibcode:2018NatCo...9.2829L. doi:10.1038/s41467-018-05286-2. PMC 6053364. PMID 30026490.

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