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Scaffold protein B
procapsid of bacteriophage phix174
Identifiers
Symbol	Phage_B
Pfam	PF02304
InterPro	IPR003513
SCOP2	1cd3 / SCOPe / SUPFAM
Available protein structures: Pfam   structures / ECOD   PDB RCSB PDB; PDBe; PDBj PDBsum structure summary

Bacteriophage scaffolding protein D
gpd prior to capsid assembly
Identifiers
Symbol	gpD
Pfam	PF02925
InterPro	IPR004196
SCOP2	1al0 / SCOPe / SUPFAM
Available protein structures: Pfam   structures / ECOD   PDB RCSB PDB; PDBe; PDBj PDBsum structure summary

In molecular biology, bacteriophage scaffolding proteins are proteins involved in bacteriophage assembly.

The assembly of a macromolecular structure proceeds via a specific pathway of ordered events and involves conformational changes in the proteins as they join the assembly. The assembly process is aided by scaffolding proteins, which act as chaperones. In bacteriophage, scaffolding proteins B and D are responsible for procapsid formation. 240 copies of protein D form the external scaffold, while 60 copies of protein B form the internal scaffold. The role of scaffolding protein D is in the production of viral single-stranded RNA.

References

1. Dokland T, McKenna R, Ilag LL, Bowman BR, Incardona NL, Fane BA, Rossmann MG (September 1997). "Structure of a viral procapsid with molecular scaffolding". Nature. 389 (6648): 308–13. doi:10.1038/38537. PMID 9305849. S2CID 4387862.

• Protein domains