Big 12 may refer to:
- Big 12 Conference, a college athletic conference
- Big Twelve Conference (Illinois), a high school conference in Central Illinois
- Northern Illinois Big 12 Conference, a high school conference in Northeastern Illinois
- G-12 (Brazilian football) or Big Twelve, a group of Brazilian football clubs
If an internal link led you here, you may wish to change the link to point directly to the intended article. Category: