Main article: Boxing at the 2010 South American Games
The Men's 48 kg event at the 2010 South American Games had its quarterfinals held on March 22, the semifinals on March 24 and the final on March 27.
Medalists
| Gold | Silver | Bronze |
Arles Contreras Colombia
|
Carlos Pilataxi Ecuador
|
Percy Pena Mori PeruEduard Bermúdez  Venezuela
|
Results
| Quarterfinals | Semifinals | Final | |||||||||
| Percy Pena Mori (PER)
| 3 | ||||||||||
| Arles Contreras (COL)
| 15 | ||||||||||
 Paulo Carvalho (BRA)
| 13 | ||||||||||
| Arles Contreras (COL)
| 15 | ||||||||||
| Arles Contreras (COL)
| +5 | ||||||||||
| Carlos Pilataxi (ECU)
| 5 | ||||||||||
 Gilberto Pedroza (PAN)
| 2 | ||||||||||
| Carlos Pilataxi (ECU)
| 7 | ||||||||||
| Carlos Pilataxi (ECU)
| 6 | ||||||||||
| Eduard Bermúdez (VEN)
| 4 | ||||||||||
| Eduard Bermúdez (VEN)
| 12 | ||||||||||
 Junior Zárate (ARG)
| 0 | ||||||||||