Ambuphylline - Misplaced Pages

(Redirected from Bufylline)

Ambuphylline
Names

IUPAC name 1,3-dimethyl-7H-purine-2,6-dione : 2-amino-2-methylpropan-1-ol
Other names Theophylline aminoisobutanol, bufylline
Identifiers
CAS Number	5634-34-4
3D model (JSmol)	Interactive image
ChEMBL	ChEMBL2104089
ChemSpider	20536
ECHA InfoCard	100.024.616
KEGG	D02884
PubChem CID	21850
UNII	VOU5V0B772
CompTox Dashboard (EPA)	DTXSID60204880
InChI InChI=1S/C7H8N4O2.C4H11NO/c1-10-5-4(8-3-9-5)6(12)11(2)7(10)13;1-4(2,5)3-6/h3H,1-2H3,(H,8,9);6H,3,5H2,1-2H3Key: SEIRRUDMPNNSCY-UHFFFAOYSA-N InChI=1/C7H8N4O2.C4H11NO/c1-10-5-4(8-3-9-5)6(12)11(2)7(10)13;1-4(2,5)3-6/h3H,1-2H3,(H,8,9);6H,3,5H2,1-2H3Key: SEIRRUDMPNNSCY-UHFFFAOYAX
SMILES O=C2N(c1ncc1C(=O)N2C)C.OCC(N)(C)C
Properties
Chemical formula	C₁₁H₁₉N₅O₃
Molar mass	269.30 g/mol
Appearance	Crystalline, slightly yellowish white powder
Melting point	254 to 256 °C (489 to 493 °F; 527 to 529 K)
Solubility in water	Freely soluble.
Pharmacology
ATC code	R03DA10 (WHO)
Except where otherwise noted, data are given for materials in their standard state (at 25 °C , 100 kPa). N verify (what is ?) Infobox references

Chemical compound

Ambuphylline (or bufylline) is a combination of theophylline and aminoisobutanol used as a bronchodilator. It also acts and may be used as a diuretic.

References

Smith, J. R.; Jensen, J. (1946). "The effect of theophylline aminoisobutanol in the failing experimental heart". The Journal of Laboratory and Clinical Medicine. 31: 455–457. PMID 21022557.
Dictionary querymondofacto.com Archived 4 March 2016 at the Wayback Machine

Short-acting β₂ agonists	Bitolterol Carbuterol Fenoterol Isoetarine Pirbuterol Procaterol Reproterol Rimiterol Salbutamol (albuterol)/Levosalbutamol (levalbuterol) Terbutaline Tulobuterol
Long-acting β₂ agonists	Bambuterol Clenbuterol Formoterol/Arformoterol Salmeterol
Ultra-long-acting β₂ agonists	Abediterol Carmoterol Indacaterol Olodaterol Vilanterol
Other	Clorprenaline Ephedrine (+theophylline, +theophylline/phenobarbital, theophylline/hydroxyzine) Epinephrine Etafedrine Hexoprenaline Isoprenaline (isoproterenol) Methylephedrine Orciprenaline (metaproterenol) Racephedrine

Eicosanoid inhibition

Leukotriene antagonists	Montelukast Pranlukast Zafirlukast
Arachidonate 5-lipoxygenase inhibitors	Zileuton
Thromboxane receptor antagonists	Ramatroban Seratrodast
Non-xanthine PDE4 inhibitors	Ibudilast Roflumilast

Others/unknown

Combination products

This drug article relating to the respiratory system is a stub. You can help Misplaced Pages by expanding it.