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Collectin-10

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(Redirected from COLEC10) Mammalian protein found in humans
COLEC10
Identifiers
AliasesCOLEC10, CLL1, CL-34, collectin subfamily member 10, 3MC3, CL-10
External IDsOMIM: 607620; MGI: 3606482; HomoloGene: 31381; GeneCards: COLEC10; OMA:COLEC10 - orthologs
Gene location (Human)
Chromosome 8 (human)
Chr.Chromosome 8 (human)
Chromosome 8 (human)Genomic location for COLEC10Genomic location for COLEC10
Band8q24.12Start118,995,452 bp
End119,108,455 bp
Gene location (Mouse)
Chromosome 15 (mouse)
Chr.Chromosome 15 (mouse)
Chromosome 15 (mouse)Genomic location for COLEC10Genomic location for COLEC10
Band15 D1|15 21.15 cMStart54,274,170 bp
End54,329,754 bp
RNA expression pattern
Bgee
HumanMouse (ortholog)
Top expressed in
  • right lobe of liver

  • testicle

  • stromal cell of endometrium

  • gonad

  • right lung

  • gallbladder

  • left ventricle

  • islet of Langerhans

  • apex of heart

  • right coronary artery
Top expressed in
  • migratory enteric neural crest cell

  • liver

  • left lobe of liver

  • yolk sac

  • small intestine

  • ileum

  • duodenum

  • abdominal wall

  • jejunum

  • Paneth cell
More reference expression data
BioGPS
n/a
Gene ontology
Molecular function
Cellular component
Biological process
Sources:Amigo / QuickGO
Orthologs
SpeciesHumanMouse
Entrez

10584

239447

Ensembl

ENSG00000184374

ENSMUSG00000038591

UniProt

Q9Y6Z7

Q8CF98

RefSeq (mRNA)

NM_006438
NM_001324095

NM_173422

RefSeq (protein)

NP_001311024
NP_006429

NP_775598

Location (UCSC)Chr 8: 119 – 119.11 MbChr 15: 54.27 – 54.33 Mb
PubMed search
Wikidata
View/Edit HumanView/Edit Mouse

Collectin-10, also known as collectin liver 1, is a collectin protein that in humans is encoded by the COLEC10 gene. Its structure is similar to mannan-binding lectin (MBL).

Collectin liver 1 (CL-L1) show very similar carbohydrate selectivity as MBL. Two other discovered collectins include collectin placenta 1 (CL-P1) and collectin kidney 1 (CL-K1). CL-L1's location found to be on chromosome 8 q23-24.1. Research concluded CL-L1 to be a serum protein.

References

  1. ^ GRCh38: Ensembl release 89: ENSG00000184374Ensembl, May 2017
  2. ^ GRCm38: Ensembl release 89: ENSMUSG00000038591Ensembl, May 2017
  3. "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  4. "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  5. Laursen TL, Sandahl TD, Støy S, Schiødt FV, Lee WM, Vilstrup H, Thiel S, Grønbaek H (March 2015). "Circulating mannan-binding lectin, M-, L-, H-ficolin and collectin-liver-1 levels in patients with acute liver failure". Liver International. 35 (3): 756–63. doi:10.1111/liv.12682. PMC 4329085. PMID 25203057.
  6. Axelgaard E, Jensen L, Dyrlund TF, Nielsen HJ, Enghild JJ, Thiel S, Jensenius JC (August 2013). "Investigations on collectin liver 1". The Journal of Biological Chemistry. 288 (32): 23407–20. doi:10.1074/jbc.M113.492603. PMC 3743509. PMID 23814060.

External links

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