Cherson (or Kherson) may refer to the following places and jurisdictions :
- Kherson, a city in southern Ukraine, the administrative center of the Kherson Oblast (province)
- Chersonesus Taurica, an ancient Greek colony founded approximately 2,500 years ago in the southwestern part of Crimea
- Cherson (theme), a Byzantine military province located in the southern Crimea, centred at Chersonesus Taurica
- the former Roman Catholic Diocese of Cherson (renamed Tiraspol), in and around post-Soviet Moldavia
- 2701 Cherson, a main-belt asteroid discovered on 1 September 1978 by Nikolai Chernykh
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