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Chlodantane

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Adaptogen drug that was never marketed

Pharmaceutical compound
Chlodantane
Clinical data
Other namesADK-910; Chlodantan; N-(2-Adamantyl)-N-(para-chlorobenzoyl)amine; 2-(para-Chlorobenzoylamino)adamantane
Identifiers
IUPAC name
  • N-(2-adamantyl)-4-chlorobenzamide
PubChem CID
ChemSpider
Chemical and physical data
FormulaC17H20ClNO
Molar mass289.80 g·mol
3D model (JSmol)
SMILES
  • C1C2CC3CC1CC(C2)C3NC(=O)C4=CC=C(C=C4)Cl
InChI
  • InChI=1S/C17H20ClNO/c18-15-3-1-12(2-4-15)17(20)19-16-13-6-10-5-11(8-13)9-14(16)7-10/h1-4,10-11,13-14,16H,5-9H2,(H,19,20)
  • Key:VOHIYJJUKAUCCU-UHFFFAOYSA-N

Chlodantane (developmental code name ADK-910) is a drug described as an adaptogen or actoprotector "of the estrogen activity type" that was developed in Russia and was never marketed. It is an adamantane derivative and is closely related to bromantane (N-(2-adamantyl)-N-(para-bromophenyl)amine) and other adamantanes. It has been said to improve physical performance. However, only animal or cell culture research has been conducted and it has not been studied in humans. The drug is described as having a broader spectrum of activity than bromantane. It also has immunostimulant effects that are said to be more pronounced than those of bromantane.

See also

References

  1. ^ Morozov IS, Ivanova IA, Lukicheva TA (2001). "Actoprotector and Adaptogen Properties of Adamantane Derivatives (A Review)". Pharmaceutical Chemistry Journal. 35 (5): 235–238. doi:10.1023/A:1011905302667.
  2. ^ Oliynyk S, Oh S (September 2012). "The pharmacology of actoprotectors: practical application for improvement of mental and physical performance". Biomolecules & Therapeutics. 20 (5): 446–456. doi:10.4062/biomolther.2012.20.5.446. PMC 3762282. PMID 24009833.
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