Columbia Building may refer to:
- in the United States
(by state)
- Columbian Building, Topeka, Kansas, listed on the NRHP in Kansas
- Columbia Building (Louisville, Kentucky)
- Columbia Building (Kansas City, Missouri), listed on the NRHP in Missouri
- Columbia Building (Columbus, Ohio), listed on the NRHP in Ohio
See also
- Columbia Hall (disambiguation)
- Columbian School (disambiguation)
- Columbia Historic District (disambiguation)
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