DDF may refer to:
Biology and medicine
- Digestive Disorders Foundation, a British medical research charity
- (N,N-dimethyl-amino)-benzenediazonium-fluoroborate, a photoaffinity probe that competes with acetylcholine for receptor binding
- Sulfoxone, an anti-leprosy drug sold under “DDF” brand
Technology
- Digital distribution frame, a device which terminates digital data streams, allowing arbitrary interconnections to be made
- 4,4'-Dinitro-3,3'-diazenofuroxan, an experimental high explosive
- Disk Data Format, a structure describing how data is formatted across disks in a RAID group
Other uses
- Demographic Development Fund, Georgian think tank
- Dicastery for the Doctrine of the Faith, a Rome-based Catholic institution
- Drop Dead Fred, a 1991 fantasy comedy film
- Dubai Duty Free, a duty-free retailer
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