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ECD (gene)

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Protein-coding gene in the species Homo sapiens
ECD
Identifiers
AliasesECD, GCR2, HSGT1, SGT1, ecdysoneless cell cycle regulator
External IDsOMIM: 616464; MGI: 1917851; HomoloGene: 5256; GeneCards: ECD; OMA:ECD - orthologs
Gene location (Human)
Chromosome 10 (human)
Chr.Chromosome 10 (human)
Chromosome 10 (human)Genomic location for ECDGenomic location for ECD
Band10q22.2Start73,130,155 bp
End73,169,055 bp
Gene location (Mouse)
Chromosome 14 (mouse)
Chr.Chromosome 14 (mouse)
Chromosome 14 (mouse)Genomic location for ECDGenomic location for ECD
Band14|14 A3Start20,369,920 bp
End20,398,189 bp
RNA expression pattern
Bgee
HumanMouse (ortholog)
Top expressed in
  • sural nerve

  • Achilles tendon

  • islet of Langerhans

  • ganglionic eminence

  • tendon of biceps brachii

  • popliteal artery

  • tibial arteries

  • ventricular zone

  • testicle

  • stromal cell of endometrium
Top expressed in
  • internal carotid artery

  • external carotid artery

  • Rostral migratory stream

  • fetal liver hematopoietic progenitor cell

  • spermatocyte

  • epiblast

  • primitive streak

  • hair follicle

  • lacrimal gland

  • parotid gland
More reference expression data
BioGPS
More reference expression data
Gene ontology
Molecular function
Cellular component
Biological process
Sources:Amigo / QuickGO
Orthologs
SpeciesHumanMouse
Entrez

11319

70601

Ensembl

ENSG00000122882

ENSMUSG00000021810

UniProt

O95905

Q9CS74

RefSeq (mRNA)

NM_001135752
NM_001135753
NM_007265

NM_027475

RefSeq (protein)

NP_001129224
NP_001129225
NP_009196

NP_081751

Location (UCSC)Chr 10: 73.13 – 73.17 MbChr 14: 20.37 – 20.4 Mb
PubMed search
Wikidata
View/Edit HumanView/Edit Mouse

Protein SGT1 is a protein that in humans is encoded by the ECD gene.

References

  1. ^ GRCh38: Ensembl release 89: ENSG00000122882Ensembl, May 2017
  2. ^ GRCm38: Ensembl release 89: ENSMUSG00000021810Ensembl, May 2017
  3. "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  4. "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  5. Sato T, Jigami Y, Suzuki T, Uemura H (Feb 1999). "A human gene, hSGT1, can substitute for GCR2, which encodes a general regulatory factor of glycolytic gene expression in Saccharomyces cerevisiae". Mol Gen Genet. 260 (6): 535–40. doi:10.1007/s004380050926. PMID 9928932. S2CID 28511451.
  6. Gaziova I, Bonnette PC, Henrich VC, Jindra M (May 2004). "Cell-autonomous roles of the ecdysoneless gene in Drosophila development and oogenesis". Development. 131 (11): 2715–25. doi:10.1242/dev.01143. PMID 15128659.
  7. "Entrez Gene: ECD ecdysoneless homolog (Drosophila)".

Further reading


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