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EFASI RNA motif

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EFASI
Consensus secondary structure and sequence conservation of EFASI RNA
Identifiers
SymbolEFASI
RfamRF02957
Other data
RNA typeGene; sRNA
SOSO:0001263
PDB structuresPDBe

The Enterobactericaea, Frequently Around STAXI and Integrases (EFASI RNA motif) is a conserved RNA structure that was discovered by bioinformatics. EFASI motifs are found in some organisms in the lineage Enterobacteriaceae.

EFASI RNAs likely function in trans as small RNAs. Many EFASI RNAs are found downstream of STAXI RNA motif examples and upstream of integrase-encoding genes, and the distance between the motifs is several hundred base pairs. Although this association likely relates to the function of EFASI RNAs, this function is not yet known.

References

  1. Weinberg Z, Lünse CE, Corbino KA, Ames TD, Nelson JW, Roth A, Perkins KR, Sherlock ME, Breaker RR (October 2017). "Detection of 224 candidate structured RNAs by comparative analysis of specific subsets of intergenic regions". Nucleic Acids Res. 45 (18): 10811–10823. doi:10.1093/nar/gkx699. PMC 5737381. PMID 28977401.
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