ENU (N-ethyl-N-nitrosourea) is a mutagen.
Enu or ENU may also refer to:
- Akanu Ibiam International Airport, serving Enugu, Nigeria
- East north up, a geographical system of Local tangent plane coordinates
- Enu language, a language of China
- L. N. Gumilyov Eurasian National University, in Kazakhstan
- Enu Island, one of the Bissagos Islands
- Enu Island, an island of Indonesia
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