Misplaced Pages

Ent-kaurenoic acid oxidase (EC 1.14.13.79) is an enzyme with systematic name ent-kaur-16-en-19-oate,NADPH:oxygen oxidoreductase (hydroxylating). This enzyme catalyses the following chemical reaction

ent-kaur-16-en-19-oate + 3 NADPH + 3 H + 3 O₂ ${\displaystyle \rightleftharpoons }$ gibberellin A12 + 3 NADP + 4 H₂O (overall reaction)

(1a) ent-kaur-16-en-19-oate + NADPH + H + O₂ ${\displaystyle \rightleftharpoons }$ ent-7alpha-hydroxykaur-16-en-19-oate + NADP + H₂O

(1b) ent-7alpha-hydroxykaur-16-en-19-oate + NADPH + H + O₂ ${\displaystyle \rightleftharpoons }$ gibberellin A12 aldehyde + NADP + 2 H₂O

(1c) gibberellin A12 aldehyde + NADPH + H + O₂ ${\displaystyle \rightleftharpoons }$ gibberellin A12 + NADP + H₂O

Ent-kaurenoic acid oxidase requires cytochrome P450.

References

1. Helliwell CA, Chandler PM, Poole A, Dennis ES, Peacock WJ (February 2001). "The CYP88A cytochrome P450, ent-kaurenoic acid oxidase, catalyzes three steps of the gibberellin biosynthesis pathway". Proceedings of the National Academy of Sciences of the United States of America. 98 (4): 2065–70. doi:10.1073/pnas.041588998. PMC 29382. PMID 11172076.

External links

• Ent-kaurenoic+acid+oxidase at the U.S. National Library of Medicine Medical Subject Headings (MeSH)

• Biology

This enzyme-related article is a stub. You can help Misplaced Pages by expanding it.

• v
• t
• e

• EC 1.14.13
• Enzyme stubs