Misplaced Pages

FAM177A1

Article snapshot taken from[REDACTED] with creative commons attribution-sharealike license. Give it a read and then ask your questions in the chat. We can research this topic together.
Protein-coding gene in the species Homo sapiens
FAM177A1
Identifiers
AliasesFAM177A1, C14orf24, family with sequence similarity 177 member A1
External IDsHomoloGene: 27852; GeneCards: FAM177A1; OMA:FAM177A1 - orthologs
Gene location (Human)
Chromosome 14 (human)
Chr.Chromosome 14 (human)
Chromosome 14 (human)Genomic location for FAM177A1Genomic location for FAM177A1
Band14q13.2Start35,044,907 bp
End35,113,130 bp
RNA expression pattern
Bgee
HumanMouse (ortholog)
Top expressed in
  • Achilles tendon

  • myocardium of left ventricle

  • left testis

  • right testis

  • corpus callosum

  • C1 segment

  • mucosa of transverse colon

  • rectum

  • right lung

  • upper lobe of left lung
    n/a
More reference expression data
BioGPS
n/a
Orthologs
SpeciesHumanMouse
Entrez

283635

n/a

Ensembl

ENSG00000151327

n/a

UniProt

Q8N128

n/a

RefSeq (mRNA)

NM_173607
NM_001079519
NM_001289022

n/a

RefSeq (protein)

NP_001072987
NP_001275951
NP_775878

n/a

Location (UCSC)Chr 14: 35.04 – 35.11 Mbn/a
PubMed searchn/a
Wikidata
View/Edit Human

Family with sequence similarity 177 member A1 (FAM177A1) is a protein that in humans is encoded by the FAM177A1 gene, previously known as C14orf24. The other member of this family is FAM177B.

Function

FAM177A1 has been linked to immune system regulation and to neurogenesis.

Interactions

IntAct reports physical interactions between FAM117A1 and these other human proteins:

References

  1. ^ GRCh38: Ensembl release 89: ENSG00000151327Ensembl, May 2017
  2. "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  3. "FAM177A1 family with sequence similarity 177 member A1 [Homo sapiens (human)] - Gene - NCBI". www.ncbi.nlm.nih.gov. Retrieved 2022-08-24.
  4. Liao, Bo-Wei; Zhang, Hong-Yan; Du, Wen-Tian; Ran, Yong; Wang, Yan-Yi; Xu, Zhi-Sheng (2021-12-15). "FAM177A1 Inhibits IL-1β-Induced Signaling by Impairing TRAF6-Ubc13 Association". Journal of Immunology. 207 (12): 3090–3097. doi:10.4049/jimmunol.2100561. ISSN 1550-6606. PMID 34799425. S2CID 244428716.
  5. Ko, Hae Young; Lee, Dong Soo; Kim, Soonhag (2009-08-08). "Noninvasive imaging of microRNA124a-mediated repression of the chromosome 14 ORF 24 gene during neurogenesis". The FEBS Journal. 276 (17): 4854–4865. doi:10.1111/j.1742-4658.2009.07185.x. ISSN 1742-4658. PMID 19663910. S2CID 205881038.
  6. Alazami, Anas M.; Patel, Nisha; Shamseldin, Hanan E.; Anazi, Shamsa; Al-Dosari, Mohammed S.; Alzahrani, Fatema; Hijazi, Hadia; Alshammari, Muneera; Aldahmesh, Mohammed A.; Salih, Mustafa A.; Faqeih, Eissa; Alhashem, Amal; Bashiri, Fahad A.; Al-Owain, Mohammed; Kentab, Amal Y. (2015-01-13). "Accelerating novel candidate gene discovery in neurogenetic disorders via whole-exome sequencing of prescreened multiplex consanguineous families". Cell Reports. 10 (2): 148–161. doi:10.1016/j.celrep.2014.12.015. ISSN 2211-1247. PMID 25558065.
  7. "IntAct Portal". www.ebi.ac.uk. Retrieved 2022-08-26.

External links


Stub icon

This protein-related article is a stub. You can help Misplaced Pages by expanding it.

Categories:
FAM177A1 Add topic