Protein-coding gene in the species Homo sapiens
Family with sequence similarity 177 member A1 (FAM177A1) is a protein that in humans is encoded by the FAM177A1 gene , previously known as C14orf24. The other member of this family is FAM177B .
Function
FAM177A1 has been linked to immune system regulation and to neurogenesis.
Interactions
IntAct reports physical interactions between FAM117A1 and these other human proteins:
References
^ GRCh38: Ensembl release 89: ENSG00000151327 – Ensembl , May 2017
"Human PubMed Reference:" . National Center for Biotechnology Information, U.S. National Library of Medicine .
"FAM177A1 family with sequence similarity 177 member A1 [Homo sapiens (human)] - Gene - NCBI" . www.ncbi.nlm.nih.gov . Retrieved 2022-08-24.
Liao, Bo-Wei; Zhang, Hong-Yan; Du, Wen-Tian; Ran, Yong; Wang, Yan-Yi; Xu, Zhi-Sheng (2021-12-15). "FAM177A1 Inhibits IL-1β-Induced Signaling by Impairing TRAF6-Ubc13 Association" . Journal of Immunology . 207 (12): 3090–3097. doi :10.4049/jimmunol.2100561 . ISSN 1550-6606 . PMID 34799425 . S2CID 244428716 .
Ko, Hae Young; Lee, Dong Soo; Kim, Soonhag (2009-08-08). "Noninvasive imaging of microRNA124a-mediated repression of the chromosome 14 ORF 24 gene during neurogenesis" . The FEBS Journal . 276 (17): 4854–4865. doi :10.1111/j.1742-4658.2009.07185.x . ISSN 1742-4658 . PMID 19663910 . S2CID 205881038 .
Alazami, Anas M.; Patel, Nisha; Shamseldin, Hanan E.; Anazi, Shamsa; Al-Dosari, Mohammed S.; Alzahrani, Fatema; Hijazi, Hadia; Alshammari, Muneera; Aldahmesh, Mohammed A.; Salih, Mustafa A.; Faqeih, Eissa; Alhashem, Amal; Bashiri, Fahad A.; Al-Owain, Mohammed; Kentab, Amal Y. (2015-01-13). "Accelerating novel candidate gene discovery in neurogenetic disorders via whole-exome sequencing of prescreened multiplex consanguineous families" . Cell Reports . 10 (2): 148–161. doi :10.1016/j.celrep.2014.12.015 . ISSN 2211-1247 . PMID 25558065 .
"IntAct Portal" . www.ebi.ac.uk . Retrieved 2022-08-26.
External links
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FAM177A1
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