The fight-or-flight response is a biological response of humans and other animals to acute stressors.
Fight or Flight may also refer to:
- Fight or Flight (2007 film), a documentary film
- Fight or Flight (2025 film), a British action film
- Fight or Flight, a 1996 book documenting battles from the soldier's perspective by military historian Geoffrey Regan
Music
- Fight or Flight (EP), a 2000 EP by Turin Brakes
- Fight or Flight (Emily Osment album)
- Fight or Flight (Hoobastank album), 2012
- Fight or Flight?, a 2006 album by Canadian jazz and soul vocalist Kellylee Evans
- Fight or Flight (band), American hard rock band
Television
- "Fight or Flight" (Burn Notice), an episode of the USA Network television show Burn Notice
- "Fight or Flight" (Heroes), a 2007 episode of the science fiction television series Heroes
- "Fight or Flight" (Modern Family), an episode of the television series Modern Family
- "Fight or Flight" (The Punisher), an episode of The Punisher
- "Fight or Flight" (QI), an episode of the comedy panel-game series QI
- "Fight or Flight" (Star Trek: Enterprise), a 2001 first-season episode of Star Trek: Enterprise
- "Fight or Flight" (Supergirl), an episode of the CBS television series Supergirl
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