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Fluocortolone

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Chemical compound Not to be confused with Fluclorolone or Fluocortin. Pharmaceutical compound
Fluocortolone
Clinical data
Other names(6S,8S,9R,10S,11S,13S,14S,16R,17S)-6-fluoro-11-hydroxy-17-(2-hydroxyacetyl)-10,13,16-trimethyl-6,7,8,9,11,12,14,15,16,17-decahydrocyclopentaphenanthren-3-one
Routes of
administration
Ointment, suppositories
ATC code
Identifiers
IUPAC name
  • (1S,2R,8S,10S,11S,13R,14S,15S,17S)-8-fluoro-17-hydroxy-14-(2-hydroxyacetyl)-2,13,15-trimethyltetracycloheptadeca-3,6-dien-5-one
CAS Number
PubChem CID
DrugBank
ChemSpider
UNII
KEGG
ChEMBL
CompTox Dashboard (EPA)
ECHA InfoCard100.005.284 Edit this at Wikidata
Chemical and physical data
FormulaC22H29FO4
Molar mass376.468 g·mol
3D model (JSmol)
SMILES
  • O=C\1\C=C/4(/C(=C/1)(F)C24(O)C3((C(=O)CO)(C23)C)C)C
InChI
  • InChI=1S/C22H29FO4/c1-11-6-14-13-8-16(23)15-7-12(25)4-5-21(15,2)20(13)17(26)9-22(14,3)19(11)18(27)10-24/h4-5,7,11,13-14,16-17,19-20,24,26H,6,8-10H2,1-3H3/t11-,13+,14+,16+,17+,19-,20-,21+,22+/m1/s1
  • Key:GAKMQHDJQHZUTJ-ULHLPKEOSA-N
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Fluocortolone is a glucocorticoid used in the treatment of several conditions, including hemorrhoids.

It is similar to fluocortin, but with one less carbonyl group.

See also

References

  1. Munro DD, Wilson HT, Rhodes EL (November 1967). "Comparison of betamethasone 17-valerate ointment with fluocortolone and fluocortolone caproate ointment". British Medical Journal. 4 (5574): 275–6. doi:10.1136/bmj.4.5574.275. PMC 1748932. PMID 6054003.


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Glucocorticoids and antiglucocorticoids
Mineralocorticoid receptor modulators
List of corticosteroids
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