Gladkov (Russian: Гладков) is a Russian surname, and may refer to:
- Aleksandr Vasilyevich Gladkov (general) (1902–1969), Soviet general and Hero of the Soviet Union
- Fyodor Gladkov, socialist writer
- Grigory Gladkov, Soviet and Russian bard and composer.
- Gennady Gladkov, Soviet and Russian composer
- Nikolai Alekseievich Gladkov, Russian ornithologist
- Yury Gladkov, St. Petersburg politician
- Vyacheslav Gladkov, Russian politician
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