Golyshev (Russian: Голышев) is a Russian masculine surname, its feminine counterpart is Golysheva. It may refer to:
- Anatoly Golyshev (born 1995), Russian ice hockey forward
- Dmitri Golyshev (born 1985), Russian football player
- Pavel Golyshev (born 1987), Russian football player, brother of Dimitri
- Viktor Golyshev (born 1937), English-to-Russian translator
- Yefim Golyshev (1897–1970), Ukrainian-born painter
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