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ITLN2
Identifiers
Aliases	ITLN2, HL-2, HL2, intelectin 2
External IDs	OMIM: 609874; HomoloGene: 135852; GeneCards: ITLN2; OMA:ITLN2 - orthologs
Gene location (Human) Chr. Chromosome 1 (human) Band 1q23.3 Start 160,945,025 bp End 160,954,809 bp
RNA expression pattern Bgee Human Mouse (ortholog) Top expressed in duodenum right lung upper lobe of left lung right coronary artery gonad left coronary artery left ovary right ovary right auricle rectum n/a More reference expression data BioGPS n/a
Orthologs Species Human Mouse Entrez 142683 n/a Ensembl ENSG00000158764 n/a UniProt Q8WWU7 n/a RefSeq (mRNA) NM_080878 n/a RefSeq (protein) NP_543154 n/a Location (UCSC) Chr 1: 160.95 – 160.95 Mb n/a PubMed search n/a
Wikidata
View/Edit Human

Intelectin 2 is a protein that in humans is encoded by the ITLN2 gene.

Human intelectin-2 has non-conserved ligand binding site substitutions compared to human intelectin-1, thus these two intelectins may not have the same metal ion requirements and ligand specificity. Likewise, there are also ligand binding site residue variations between human and mouse intelectin-2 with no known biochemical and functional consequences.

See also

• Intelectin

References

1. ^ GRCh38: Ensembl release 89: ENSG00000158764 – Ensembl, May 2017
2. "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
3. "Entrez Gene: Intelectin 2". Retrieved 2016-02-25.
4. Wangkanont K, Wesener DA, Vidani JA, Kiessling LL, Forest KT (March 2016). "Structures of Xenopus Embryonic Epidermal Lectin Reveal a Conserved Mechanism of Microbial Glycan Recognition". The Journal of Biological Chemistry. 291 (11): 5596–610. doi:10.1074/jbc.M115.709212. PMC 4786701. PMID 26755729.

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