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Isolation is the near or complete lack of social contact by an individual.

Isolation or isolated may also refer to:

Sociology and psychology

Social isolation
Isolation (psychology), a defense mechanism in psychoanalytic theory
Emotional isolation, a feeling of isolation despite a functioning social network
Isolation effect, a psychological effect of distinctive items more easily remembered

Real-root isolation
Isolation lemma, a technique used to reduce the number of solutions to a computational problem.
Isolated point, a topological notion of having no points near a given point

Electrical or galvanic isolation, isolating functional sections of electrical systems to prevent current flowing between them
An isolated system, a system without any external exchange
Isolating language, a type of language with a low morpheme-per-word ratio
Isolation (microbiology), techniques to separate microbes from a sample containing mixtures of microbes
Reproductive isolation, in population genetics, prevents members of two different species from producing offspring if they cross or mate
Topographic isolation of a summit, the great circle distance to the nearest point of equal elevation

In electronics, a measure of how well two ports are disconnected in devices such as directional couplers and circulators
Isolation (database systems), how and when the changes made by one operation become visible to other concurrent operations
In computer security, another name for software sandboxing
Vibration isolation, in engineering, the process of isolating an object from the source of vibrations

Isolation (2005 film), an Irish horror film
Isolation (2009 film), a British documentary
Isolation, a 2015 drama film featuring Dominic Purcell, Stephen Lang, and Tricia Helfer
"Isolation" (The Walking Dead), an episode of the television series The Walking Dead

Isolation (board game), a 1972 board game
Isolation (illusion), an illusion whereby a prop appears to float in space
Isolation (novel), a 2012 novella by Dan Wells
Isolation (poker), a play specifically for the purpose of making the hand a one-on-one contest with a specific opponent

Isolation (health care), various measures taken to prevent contagious diseases from being spread
Mount Isolation, New Hampshire, United States