James Otis may refer to:
- James Otis Sr. (1702–1778), Massachusetts lawyer and public official
- James Otis Jr. (1725–1783), American revolutionary politician from Massachusetts
- James Otis (mayor) (1826–1875), mayor of San Francisco, California
- James Otis (New York politician) (1836–1898), member of the New York State Senate and a society leader during the Gilded Age
- James C. Otis (1912–1993), Justice of the Minnesota Supreme Court
- James Otis (actor) (1943–2020), American film and television actor
- Jim Otis (born 1948), American football player
- James Otis, pen name of James Otis Kaler (1848–1912), American journalist and children's author
Topics referred to by the same termThis disambiguation page lists articles about people with the same name. If an internal link led you here, you may wish to change the link to point directly to the intended article. Category: