Laura Spencer may refer to:
- Laura Spencer (actress) (born 1986), American actress
- Laura Spencer (General Hospital), a fictional character in the television series General Hospital
- Laura Horton (formerly Spencer), a fictional character in the television series Days of Our Lives
- Laura Spencer-Churchill, Duchess of Marlborough (1915–1990), British noblewoman and socialite
See also
- Laura Spencer Portor Pope (1872–1957), American journalist and author
- Lara Spencer (born 1969), American television journalist
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