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MRM3
Identifiers
Aliases	MRM3, RNMTL1, HC90, RMTL1, mitochondrial rRNA methyltransferase 3
External IDs	OMIM: 612600; MGI: 1914640; HomoloGene: 10033; GeneCards: MRM3; OMA:MRM3 - orthologs
Gene location (Human) Chr. Chromosome 17 (human) Band 17p13.3 Start 782,353 bp End 792,509 bp
Gene location (Mouse) Chr. Chromosome 11 (mouse) Band 11|11 B5 Start 76,134,541 bp End 76,141,445 bp
RNA expression pattern Bgee Human Mouse (ortholog) Top expressed in endothelial cell gastrocnemius muscle apex of heart muscle of thigh glutes gingival epithelium gonad body of pancreas sperm deltoid muscle Top expressed in digastric muscle interventricular septum morula sternocleidomastoid muscle temporal muscle right kidney intercostal muscle soleus muscle muscle of thigh epiblast More reference expression data BioGPS More reference expression data
Gene ontology Molecular function RNA methyltransferase activity transferase activity protein binding rRNA (guanosine-2'-O-)-methyltransferase activity RNA binding methyltransferase activity Cellular component mitochondrial matrix mitochondrion Biological process rRNA processing methylation RNA processing rRNA 2'-O-methylation Sources:Amigo / QuickGO
Orthologs Species Human Mouse Entrez 55178 67390 Ensembl ENSG00000171861 ENSMUSG00000038046 UniProt Q9HC36 Q5ND52 RefSeq (mRNA) NM_018146 NM_001317947 NM_183263 RefSeq (protein) NP_001304876 NP_060616 NP_899086 Location (UCSC) Chr 17: 0.78 – 0.79 Mb Chr 11: 76.13 – 76.14 Mb PubMed search
Wikidata
View/Edit Human View/Edit Mouse

rRNA methyltransferase 3, mitochondrial is an enzyme that in humans is encoded by the MRM3 gene.

See also

• Methyltransferase
  • RNA methyltransferase
• Mitochondrion
• MRM1, a gene encoing rRNA methyltransferase 1, mitochondrial
• MRM2
• Ribosomal RNA (rRNA)

References

1. ^ GRCh38: Ensembl release 89: ENSG00000171861 – Ensembl, May 2017
2. ^ GRCm38: Ensembl release 89: ENSMUSG00000038046 – Ensembl, May 2017
3. "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
4. "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
5. Xu J, De Zhu J, Ni M, Wan F, Gu JR (Sep 2002). "The ATF/CREB site is the key element for transcription of the human RNA methyltransferase like 1(RNMTL1) gene, a newly discovered 17p13.3 gene". Cell Res. 12 (3–4): 177–97. doi:10.1038/sj.cr.7290124. PMID 12296377.
6. "MRM3 mitochondrial rRNA methyltransferase 3 [ Homo sapiens (human) ]".

Further reading

• Maruyama K, Sugano S (1994). "Oligo-capping: a simple method to replace the cap structure of eukaryotic mRNAs with oligoribonucleotides". Gene. 138 (1–2): 171–4. doi:10.1016/0378-1119(94)90802-8. PMID 8125298.
• Suzuki Y, Yoshitomo-Nakagawa K, Maruyama K, et al. (1997). "Construction and characterization of a full length-enriched and a 5'-end-enriched cDNA library". Gene. 200 (1–2): 149–56. doi:10.1016/S0378-1119(97)00411-3. PMID 9373149.
• Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. Bibcode:2002PNAS...9916899M. doi:10.1073/pnas.242603899. PMC 139241. PMID 12477932.
• Ota T, Suzuki Y, Nishikawa T, et al. (2004). "Complete sequencing and characterization of 21,243 full-length human cDNAs". Nat. Genet. 36 (1): 40–5. doi:10.1038/ng1285. PMID 14702039.
• Ewing RM, Chu P, Elisma F, et al. (2007). "Large-scale mapping of human protein-protein interactions by mass spectrometry". Mol. Syst. Biol. 3 (1): 89. doi:10.1038/msb4100134. PMC 1847948. PMID 17353931.

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