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Major facilitator superfamily domain-containing protein 9

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Protein-coding gene in the species Homo sapiens
MFSD9
Identifiers
AliasesMFSD9, major facilitator superfamily domain containing 9
External IDsMGI: 2443548; HomoloGene: 13100; GeneCards: MFSD9; OMA:MFSD9 - orthologs
Gene location (Human)
Chromosome 2 (human)
Chr.Chromosome 2 (human)
Chromosome 2 (human)Genomic location for MFSD9Genomic location for MFSD9
Band2q12.1Start102,714,630 bp
End102,736,888 bp
Gene location (Mouse)
Chromosome 1 (mouse)
Chr.Chromosome 1 (mouse)
Chromosome 1 (mouse)Genomic location for MFSD9Genomic location for MFSD9
Band1|1 BStart40,811,198 bp
End40,829,847 bp
RNA expression pattern
Bgee
HumanMouse (ortholog)
Top expressed in
  • tendon of biceps brachii

  • mucosa of transverse colon

  • body of pancreas

  • rectum

  • paraflocculus of cerebellum

  • jejunal mucosa

  • right lobe of liver

  • bone marrow cells

  • duodenum

  • endothelial cell
Top expressed in
  • secondary oocyte

  • jejunum

  • primary oocyte

  • proximal tubule

  • lumbar spinal ganglion

  • right kidney

  • prostate

  • ileum

  • human kidney

  • large intestine
More reference expression data
BioGPS
n/a
Gene ontology
Molecular function
Cellular component
Biological process
Sources:Amigo / QuickGO
Orthologs
SpeciesHumanMouse
Entrez

84804

211798

Ensembl

ENSG00000135953

ENSMUSG00000041945

UniProt

Q8NBP5

Q8C0T7

RefSeq (mRNA)

NM_032718
NM_001322080
NM_001322081

NM_172499

RefSeq (protein)

NP_001309009
NP_001309010
NP_116107

NP_766087

Location (UCSC)Chr 2: 102.71 – 102.74 MbChr 1: 40.81 – 40.83 Mb
PubMed search
Wikidata
View/Edit HumanView/Edit Mouse

Major facilitator superfamily domain-containing protein 9 is a protein that in humans is encoded by the MFSD9 gene. It is a potential solute carrier, and called atypical solute carrier since it is not named according to the SLC nomenclature. It is expressed both in central and peripheral organs.

References

  1. ^ GRCh38: Ensembl release 89: ENSG00000135953 – Ensembl, May 2017
  2. ^ GRCm38: Ensembl release 89: ENSMUSG00000041945 – Ensembl, May 2017
  3. "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  4. "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  5. Perland E, Bagchi S, Klaesson A, Fredriksson R (September 2017). "Characteristics of 29 novel atypical solute carriers of major facilitator superfamily type: evolutionary conservation, predicted structure and neuronal co-expression". Open Biology. 7 (9): 170142. doi:10.1098/rsob.170142. PMC 5627054. PMID 28878041.
  6. Perland E, Fredriksson R (March 2017). "Classification Systems of Secondary Active Transporters". Trends in Pharmacological Sciences. 38 (3): 305–315. doi:10.1016/j.tips.2016.11.008. PMID 27939446.
  7. Perland E, Hellsten SV, Schweizer N, Arapi V, Rezayee F, Bushra M, Fredriksson R (2017). "Structural prediction of two novel human atypical SLC transporters, MFSD4A and MFSD9, and their neuroanatomical distribution in mice". PLOS ONE. 12 (10): e0186325. Bibcode:2017PLoSO..1286325P. doi:10.1371/journal.pone.0186325. PMC 5648162. PMID 29049335.


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