Marcuzzi is an Italian surname. Notable people with the surname include:
- Alessia Marcuzzi (born 1972), Italian television personality and actress
- Angelo Marcuzzi (died 1453), Roman Catholic prelate, Bishop of Telese
- Michael Marcuzzi, American visual effects artist
- SantΓ© Marcuzzi (1934β2020), French rower
- Sebastiano Marcuzzi (1725-1790) Italian abbot from Friuli and writer of texts on religion
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