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Melicopidine

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Chemical compound

Melicopidine
Names
Preferred IUPAC name 4,11-dimethoxy-5-methyl-dioxoloacridin-10-one
Identifiers
CAS Number
3D model (JSmol)
ChEBI
ChEMBL
ChemSpider
ECHA InfoCard 100.006.821 Edit this at Wikidata
EC Number
  • 207-502-0
PubChem CID
UNII
CompTox Dashboard (EPA)
InChI
  • InChI=1S/C17H15NO5/c1-18-10-7-5-4-6-9(10)13(19)11-12(18)15(21-3)17-16(14(11)20-2)22-8-23-17/h4-7H,8H2,1-3H3Key: TZZNUDMEMFBPQI-UHFFFAOYSA-N
SMILES
  • CN1C2=CC=CC=C2C(=O)C3=C1C(=C4C(=C3OC)OCO4)OC
Properties
Chemical formula C17H15NO5
Molar mass 313.309 g·mol
Hazards
Lethal dose or concentration (LD, LC):
LDLo (lowest published) 200 mg/kg (mouse)
Except where otherwise noted, data are given for materials in their standard state (at 25 °C , 100 kPa). Infobox references
Chemical compound

Melicopidine is an alkaloid. Its formula is C17H15NO5. It, along with melicopine and melicopicine, is named for the Australian rutaceae (Melicope fareana) from which it was first isolated.

Occurrence

As an alkaloid, melicopidine naturally occurs in and has been isolated from Medicosma fareana and Sarcomelicope megistophylla in addition to Melicope fareana.

References

  1. Svoboda GH, Kattau RW (1967). "Alkaloids of Acronychia Baueri (Baurella australiana) III". Lloydia. 30: 364.
  2. ^ Crow W, Price J (1949). "Alkaloids of the Australian Rutaceae: Melicope fareana. II. Preliminary Examination of Melicopine, Melicopidine, and Melicopicine". Australian Journal of Chemistry. 2 (2): 255. Bibcode:1949AuSRA...2..255C. doi:10.1071/CH9490255. ISSN 0004-9425.
  3. Habtemariam S, Waterman PG, Hartley T (September 1996). "Fareanine and fareanol from leaves of Medicosma fareana". Phytochemistry. 43 (1): 291–294. Bibcode:1996PChem..43..291H. doi:10.1016/0031-9422(96)00220-8.
  4. Mitaku S, Fokialakis N, Magiatis P, Tillequin F (February 2007). "Alkaloids from Sarcomelicope megistophylla". Fitoterapia. 78 (2): 169–170. doi:10.1016/j.fitote.2006.10.003. PMID 17207940.


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