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Methylenomycin B

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Methylenomycin B
Structural formula of methylenomycin B
Ball-and-stick model of the methylenomycin B molecule
Names
IUPAC name 2,3-Dimethyl-5-methylene-2-cyclopenten-1-one
Identifiers
CAS Number
3D model (JSmol)
ChemSpider
PubChem CID
UNII
CompTox Dashboard (EPA)
InChI
  • InChI=1S/C8H10O/c1-5-4-6(2)8(9)7(5)3/h2,4H2,1,3H3Key: YDXIEAHUYZKJOH-UHFFFAOYSA-N
  • InChI=1/C8H10O/c1-5-4-6(2)8(9)7(5)3/h2,4H2,1,3H3Key: YDXIEAHUYZKJOH-UHFFFAOYAN
SMILES
  • O=C/1\C(=C)CC(=C\1C)\C
Properties
Chemical formula C8H10O
Molar mass 122.167 g·mol
Except where otherwise noted, data are given for materials in their standard state (at 25 °C , 100 kPa). checkY verify (what is  ?) Infobox references
Chemical compound

Methylenomycin B is a cyclopentanone derived antibiotic produced by Streptomyces coelicolor A3(2) that is effective against both Gram-negative and Gram-positive bacteria. Methylenomycins are naturally produced in two variants: A and B.

See also

References

  1. Brian P, Riggle PJ, Santos RA, Champness WC (June 1996). "Global negative regulation of Streptomyces coelicolor antibiotic synthesis mediated by an absA-encoded putative signal transduction system". J. Bacteriol. 178 (11): 3221–31. doi:10.1128/jb.178.11.3221-3231.1996. PMC 178074. PMID 8655502.
  2. Hobbs G, Obanye AI, Petty J, et al. (March 1992). "An integrated approach to studying regulation of production of the antibiotic methylenomycin by Streptomyces coelicolor A3(2)". J. Bacteriol. 174 (5): 1487–94. doi:10.1128/jb.174.5.1487-1494.1992. PMC 206543. PMID 1537793.


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