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Mnt IRES

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Mnt IRES
Predicted secondary structure and sequence conservation of IRES_mnt
Identifiers
SymbolIRES_mnt
RfamRF00457
Other data
RNA typeCis-reg; IRES
Domain(s)Eukaryota
GOGO:0043022
SOSO:0000243
PDB structuresPDBe

The Mnt internal ribosome entry site (IRES) is an RNA element. Mnt is a transcriptional repressor related to the Myc/Mad family of transcription factors. It is thought that this IRES allows efficient Mnt synthesis when cap-dependent translation initiation is reduced.

See also

References

  1. Stoneley M, Spencer JP, Wright SC (February 2001). "An internal ribosome entry segment in the 5' untranslated region of the mnt gene". Oncogene. 20 (7): 893–897. doi:10.1038/sj.onc.1204157. PMID 11314024.

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