Mottola is an Italian language surname. Möttölä is a Finnish language surname. Notable people with the surnames Mottola or Möttölä include:
- Chad Mottola (born 1971), American baseball player and coach
- Greg Mottola (born 1964), American film director and screenwriter
- Hanno Möttölä (born 1976), Finnish basketball player
- Stefano Mottola, Italian astronomer
- Tommy Mottola (born 1949), music executive and co-owner of Casablanca Records
- Tony Mottola (1918–2004), American guitarist
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