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Netoglitazone

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Chemical compound Pharmaceutical compound
Netoglitazone
Clinical data
ATC code
  • None
Identifiers
IUPAC name
  • 5-naphthalen-2-yl)methyl]-1,3-thiazolidine-2,4-dione
CAS Number
PubChem CID
IUPHAR/BPS
DrugBank
ChemSpider
UNII
KEGG
CompTox Dashboard (EPA)
ECHA InfoCard100.233.314 Edit this at Wikidata
Chemical and physical data
FormulaC21H16FNO3S
Molar mass381.42 g·mol
3D model (JSmol)
SMILES
  • C1=CC=C(C(=C1)COC2=CC3=C(C=C2)C=C(C=C3)CC4C(=O)NC(=O)S4)F
InChI
  • InChI=1S/C21H16FNO3S/c22-18-4-2-1-3-16(18)12-26-17-8-7-14-9-13(5-6-15(14)11-17)10-19-20(24)23-21(25)27-19/h1-9,11,19H,10,12H2,(H,23,24,25)
  • Key:PKWDZWYVIHVNKS-UHFFFAOYSA-N
  (what is this?)  (verify)

Netoglitazone (also called MCC-555) is a hypoglycemic agent belonging to the thiazolidinedione group.

References

  1. Lazarenko OP, Rzonca SO, Suva LJ, Lecka-Czernik B (January 2006). "Netoglitazone is a PPAR-gamma ligand with selective effects on bone and fat". Bone. 38 (1): 74–84. doi:10.1016/j.bone.2005.07.008. PMC 1850100. PMID 16137931.
Oral diabetes medication, insulins and insulin analogs, and other drugs used in diabetes (A10)
Insulins / insulin analogs
fast-acting
short-acting
long-acting
ultra-long-acting
inhalable
  • Exubera
  • Afrezza
Non-insulins
Insulin sensitizers
Biguanides
TZDs/"glitazones" (PPAR)
Dual PPAR agonists
Amylin analogs and DACRAs
Secretagogues
KATP
Sulfonylureas
Meglitinides/"glinides"
GLP-1 receptor agonists
GLP1 poly-agonist peptides
DPP-4 inhibitors/"gliptins"
Other
Aldose reductase inhibitors
Alpha-glucosidase inhibitors
SGLT2 inhibitors/"gliflozins"
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Combinations
PPARTooltip Peroxisome proliferator-activated receptor modulators
PPARαTooltip Peroxisome proliferator-activated receptor alpha
PPARδTooltip Peroxisome proliferator-activated receptor delta
PPARγTooltip Peroxisome proliferator-activated receptor gamma
Non-selective
See also
Receptor/signaling modulators
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