Misplaced Pages

Norbudrine

Clinical data
Other names	Norbutrine; RD-9338; N-Cyclobutylnoradrenaline; N-Cyclobutylnorepinephrine
Drug class	Sympathomimetic; Bronchodilator
Identifiers
IUPAC name 4-benzene-1,2-diol
CAS Number	15686-81-4 13329-35-6 (hydrochloride)
PubChem CID	166575
ChemSpider	145768
UNII	8P6T83567P
ChEMBL	ChEMBL2106796
CompTox Dashboard (EPA)	DTXSID50864619
Chemical and physical data
Formula	C12H17NO3
Molar mass	223.272 g·mol
3D model (JSmol)	Interactive image
SMILES C1CC(C1)NCC(C2=CC(=C(C=C2)O)O)O
InChI InChI=1S/C12H17NO3/c14-10-5-4-8(6-11(10)15)12(16)7-13-9-2-1-3-9/h4-6,9,12-16H,1-3,7H2 Key:OVTZNVCECJYMDW-UHFFFAOYSA-N

Norbudrine (INNTooltip International Nonproprietary Name; developmental code name RD-9338), also known as norbutrine (BANTooltip British Approved Name) or as N-cyclobutylnoradrenaline, is a drug of the phenethylamine and catecholamine families described as a sympathomimetic and bronchodilator which was never marketed. It is the N-cyclobutyl analogue of norepinephrine (noradrenaline). The drug was first described in the literature by 1966.

References

1. ^ Elks J (2014). The Dictionary of Drugs: Chemical Data: Chemical Data, Structures and Bibliographies. Springer US. p. 1-PA215. ISBN 978-1-4757-2085-3. Retrieved 17 October 2024.
2. List PH, Hörhammer L (2013). Chemikalien und Drogen Teil A: N-Q. Handbuch der Pharmazeutischen Praxis - Vollständige (4.) Neuausgabe (in German). Springer Berlin Heidelberg. pp. 265–266. ISBN 978-3-642-65035-2. Retrieved 17 October 2024.
3. "-drine sympathomimetics" (PDF). The use of stems in the selection of International Nonproprietary Names (INN) for pharmaceutical substances 2018 (Stem Book 2018). World Health Organization.
4. "Norbudrine". PubChem. U.S. National Library of Medicine. Retrieved 17 October 2024.

• Abandoned drugs
• Bronchodilators
• Catecholamines
• Cyclobutyl compounds
• Phenylethanolamines
• Sympathomimetics