PGRC can refer to:
- Phased Geological Repository Concept developed by NIREX (now Nuclear Decommissioning Authority, NDA, Radioactive Waste Management, RMW) for the deep geological repository program in the United Kingdom
- Philadelphia Girls' Rowing Club
- A seedbank, including:
- Plant Genetic Resources Canada, part of Agriculture and Agri-Food Canada
- Plant Genetic Resources Centre:
- in Ethiopia, founded by Melaku Worede
- operated by the Southern African Development Community
- in Sri Lanka
- in Uganda
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