| T-lymphoblastic leukemia/lymphoma | |
|---|---|
| Other names | Precursor T-cell lymphoblastic lymphoma, Precursor T acute lymphoblastic leukemia/lymphoma |
| Specialty | Hematology, oncology |
T-lymphoblastic leukemia/lymphoma (WHO 2008), previously labeled precursor T-lymphoblastic leukemia/lymphoma (WHO 2001) is a form of lymphoid leukemia and lymphoma in which too many T-cell lymphoblasts (immature white blood cells) are found in the blood, bone marrow, and tissues, particularly mediastinal lymph nodes. Labeling as leukemia or lymphoma depends on which feature is more pronounced in a given situation, but has no biological or treatment implication.
It is uncommon in adults, but represents 15% of childhood acute lymphoblastic leukemia and 90% of lymphoblastic lymphoma.
The 2008 terminology dropped "precursor" to avoid linguistic redundancy because the lymphoblast is an immature precursor cell by definition.
References
- ^ Jaffe ES, Harris NL, Vardiman JW, Campo E, Arber, DA (2011). Hematopathology (1st ed.). Elsevier Saunders. ISBN 978-0-7216-0040-6.
- Kim MA, Lee GW, Maeng KY (August 2005). "An unusual presenting feature of precursor T-cell acute lymphoblastic leukemia/lymphoma". Ann. Hematol. 84 (8): 553–4. doi:10.1007/s00277-005-1042-4. PMID 15843931. S2CID 40149515.
- Lyman MD, Neuhauser TS (April 2002). "Precursor T-cell acute lymphoblastic leukemia/lymphoma involving the uterine cervix, myometrium, endometrium, and appendix". Ann. Diagn. Pathol. 6 (2): 125–8. doi:10.1053/adpa.2002.32381. PMID 12004362.
- Han X, Bueso-Ramos CE (April 2007). "Precursor T-cell acute lymphoblastic leukemia/lymphoblastic lymphoma and acute biphenotypic leukemias". American Journal of Clinical Pathology. 127 (4): 528–44. doi:10.1309/2QE3A6EKQ8UYDYRC. PMID 17369128.
This article incorporates public domain material from Dictionary of Cancer Terms. U.S. National Cancer Institute.
External links
| Classification | D |
|---|
- Precursor T-lymphoblastic leukemia entry in the public domain NCI Dictionary of Cancer Terms
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