Pharmaceutical compound
| Combination of | |
|---|---|
| Isoniazid | Anti-tuberculosis medication |
| Rifampicin | Anti-tuberculosis medication |
| Clinical data | |
| Trade names | IsonaRif, Rifamate, others |
| ATC code | |
| Identifiers | |
| CAS Number | |
| KEGG | |
Isoniazid/rifampicin, also known as isoniazid/rifampin, is a medication used to treat tuberculosis. It is a fixed dose combination of isoniazid and rifampicin (rifampin). It is used together with other antituberculosis medication. It is taken by mouth.
It is on the World Health Organization's List of Essential Medicines.
Adverse effects and safety
Side effects are those of the underlying medications. Common side effects include poor coordination, poor appetite, nausea, numbness, and feeling tired. More severe side effects include liver problems. Use is generally not recommended in children. It is unclear if use is safe in pregnancy.
References
- ^ World Health Organization (2009). Stuart MC, Kouimtzi M, Hill SR (eds.). WHO Model Formulary 2008. World Health Organization. p. 142. hdl:10665/44053. ISBN 9789241547659.
- World Health Organization (2019). World Health Organization model list of essential medicines: 21st list 2019. Geneva: World Health Organization. hdl:10665/325771. WHO/MVP/EMP/IAU/2019.06. License: CC BY-NC-SA 3.0 IGO.
- ^ "Isoniazid/rifampin Side Effects in Detail - Drugs.com". www.drugs.com. Archived from the original on 21 December 2016. Retrieved 18 December 2016.
- "Isoniazid / rifampin Use During Pregnancy | Drugs.com". www.drugs.com. Archived from the original on 21 December 2016. Retrieved 18 December 2016.
