Ruotolo is an Italian surname. Notable people with the surname include:
- Dolindo Ruotolo (1882–1970), Italian Roman Catholic priest
- Kade Ruotolo, American grappler and youngest-ever ADCC champion
- Gennaro Ruotolo (born 1967), Italian footballer and manager
- Onorio Ruotolo (1888–1966), Italian sculptor
- Raffaele Ruotolo (born 1965), American soccer player
- Riccardo Ruotolo (1928–2012), Italian Roman Catholic bishop
- Sandro Ruotolo (born 1955), Italian journalist and politician
See also
- Ruotolo Peak, mountain in Antarctica
- Rotolo
- Otolo
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