Saint-Claude or St. Claude can refer to:
Saints
- Claudius of Besançon (c. 607–696 or 699), French abbot
- Claude La Colombière (1641–1682), French Jesuit priest
Places
- Canada
- France
- Arrondissement of Saint-Claude, Jura
- Avignon-lès-Saint-Claude, Jura
- Saint-Claude (Besançon), Doubs
- Saint-Claude, Guadeloupe
- Saint-Claude, Jura
- Saint-Claude-de-Diray, Loir-et-Cher
- United States
- St. Claude, New Orleans, Louisiana, a neighborhood
Other uses
- "Saint Claude" (song), by Christine and the Queens
- Roman Catholic Diocese of Saint-Claude
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