Seina may refer to:
- Seina (kickboxer) (聖愛, born 2001), Japanese professional kickboxer
- Seina Nakajima (中嶋 星奈, born 1997), Japanese curler
- Seina Saito (齋藤 聖奈, born 1992), Japanese rugby union and rugby sevens player
- Seina Shimabukuro (島袋 聖南, born 1987), Japanese model and reality television contestant
See also
- Marycha (Lithuanian: Seina), a river on the Polish–Lithuanian and Lithuanian–Belarusian borders
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