Sleuth may refer to:
- Detective
- Sleuth, collective noun for a group of bears
Computing
- The Sleuth Kit, a collection of forensic analysis software
- SLEUTH assembler language for the UNIVAC 1107
Entertainment and media
- Cloo, formerly Sleuth, an American cable television channel owned by NBCUniversal
- Sleuth (Australian TV channel), formerly Fox Sleuth, an Australian cable channel owned by Foxtel
- Sleuth (Disney), a fictional Disney character
- Sleuth (video game), a 1983 computer game
Theatre and film
- The Sleuth (1925 film), a silent era film featuring Stan Laurel
- Sleuth (play), a 1970 play by Anthony Shaffer
- Sleuth (1972 film), a film adaptation of the Anthony Shaffer play, directed by Joseph L. Mankiewicz
- Sleuth (2007 film), a film adaptation of the Anthony Shaffer play, adapted by Harold Pinter and directed by Kenneth Branagh
Vessels
- HMAS Sleuth, ships of the Royal Australian Navy
- HMS Sleuth (P261), a submarine of the Royal Navy, in service 1944–1958
Other
- Sleuth (game), one of the 1960s 3M "gamette" card games
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