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TAF1D
Identifiers
Aliases	TAF1D, JOSD3, RAFI41, TAF(I)41, TAFI41, TATA-box binding protein associated factor, RNA polymerase I subunit D
External IDs	OMIM: 612823; MGI: 1922566; HomoloGene: 11472; GeneCards: TAF1D; OMA:TAF1D - orthologs
Gene location (Human) Chr. Chromosome 11 (human) Band 11q21 Start 93,729,948 bp End 93,784,391 bp
Gene location (Mouse) Chr. Chromosome 9 (mouse) Band 9|9 A2 Start 15,306,214 bp End 15,316,991 bp
RNA expression pattern Bgee Human Mouse (ortholog) Top expressed in body of pancreas visceral pleura sural nerve primary visual cortex left ovary parietal pleura anterior cingulate cortex right frontal lobe C1 segment pylorus Top expressed in Ileal epithelium genital tubercle embryo tail of embryo embryo superior surface of tongue morula morula blastocyst ectoderm More reference expression data BioGPS n/a
Gene ontology Molecular function DNA binding protein binding Cellular component RNA polymerase transcription factor SL1 complex nucleus nucleoplasm microtubule organizing center Biological process transcription initiation from RNA polymerase I promoter termination of RNA polymerase I transcription epigenetic maintenance of chromatin in transcription-competent conformation regulation of transcription, DNA-templated transcription, DNA-templated transcription elongation from RNA polymerase I promoter Sources:Amigo / QuickGO
Orthologs Species Human Mouse Entrez 79101 75316 Ensembl ENSG00000166012 ENSMUSG00000031939 UniProt Q9H5J8 Q9D4V4 RefSeq (mRNA) NM_024116 NM_026541 NM_027261 NM_029248 RefSeq (protein) NP_077021 NP_081537 NP_083524 Location (UCSC) Chr 11: 93.73 – 93.78 Mb Chr 9: 15.31 – 15.32 Mb PubMed search
Wikidata
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TATA box binding protein (TBP)-associated factor, RNA polymerase I, D, 41kDa is a protein that in humans is encoded by the TAF1D gene.

Function

TAF1D is a member of the SL1 complex, which includes TBP and TAF1A, TAF1B, and TAF1C, and plays a role in RNA polymerase I transcription.

References

1. ^ GRCh38: Ensembl release 89: ENSG00000166012 – Ensembl, May 2017
2. ^ GRCm38: Ensembl release 89: ENSMUSG00000031939 – Ensembl, May 2017
3. "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
4. "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
5. "Entrez Gene: TATA box binding protein (TBP)-associated factor, RNA polymerase I, D, 41kDa".
6. Wang L, Bhattacharyya N, Chelsea DM, Escobar PF, Banerjee S (November 2004). "A novel nuclear protein, MGC5306 interacts with DNA polymerase beta and has a potential role in cellular phenotype". Cancer Research. 64 (21): 7673–7. doi:10.1158/0008-5472.CAN-04-2801. PMID 15520167.
7. Gorski JJ, Pathak S, Panov K, Kasciukovic T, Panova T, Russell J, Zomerdijk JC (March 2007). "A novel TBP-associated factor of SL1 functions in RNA polymerase I transcription". The EMBO Journal. 26 (6): 1560–8. doi:10.1038/sj.emboj.7601601. PMC 1829371. PMID 17318177.

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