TDP-4-oxo-6-deoxy-alpha-D-glucose-3,4-oxoisomerase (dTDP-3-dehydro-6-deoxy-alpha-D-galactopyranose-forming)

TDP-4-oxo-6-deoxy-alpha-D-glucose-3,4-oxoisomerase (dTDP-3-dehydro-6-deoxy-alpha-D-galactopyranose-forming) (EC 5.3.2.3, dTDP-6-deoxy-hex-4-ulose isomerase, TDP-6-deoxy-hex-4-ulose isomerase, FdtA) is an enzyme with systematic name dTDP-4-dehydro-6-deoxy-alpha-D-glucopyranose:dTDP-3-dehydro-6-deoxy-alpha-D-galactopyranose isomerase. This enzyme catalyses the following chemical reaction

dTDP-4-dehydro-6-deoxy-alpha-D-glucopyranose

\rightleftharpoons

dTDP-3-dehydro-6-deoxy-alpha-D-galactopyranose

The enzyme is involved in the biosynthesis of dTDP-3-acetamido-3,6-dideoxy-alpha-D-galactose.

References

Pfoestl A, Hofinger A, Kosma P, Messner P (July 2003). "Biosynthesis of dTDP-3-acetamido-3,6-dideoxy-alpha-D-galactose in Aneurinibacillus thermoaerophilus L420-91T". The Journal of Biological Chemistry. 278 (29): 26410–7. doi:10.1074/jbc.m300858200. PMID 12740380.
Davis ML, Thoden JB, Holden HM (June 2007). "The x-ray structure of dTDP-4-keto-6-deoxy-D-glucose-3,4-ketoisomerase". The Journal of Biological Chemistry. 282 (26): 19227–36. doi:10.1074/jbc.m702529200. PMID 17459872.

External links

TDP-4-oxo-6-deoxy-alpha-D-glucose-3,4-oxoisomerase+(dTDP-3-dehydro-6-deoxy-alpha-D-galactopyranose-forming) at the U.S. National Library of Medicine Medical Subject Headings (MeSH)

v t e Isomerases: intramolecular oxidoreductases (EC 5.3)
5.3.1: Aldoses/Ketoses	Triosephosphate isomerase Ribose-5-phosphate isomerase Mannose phosphate isomerase Glucose isomerase
5.3.2: Keto/Enol	Phenylpyruvate tautomerase Oxaloacetate tautomerase 4-Oxalocrotonate tautomerase
5.3.3: C = C	Steroid D-isomerase Isopentenyl-diphosphate delta isomerase Vinylacetyl-CoA D-isomerase Muconolactone D-isomerase Cholestenol Delta-isomerase (EBP) Methylitaconate D-isomerase Aconitate Delta-isomerase Enoyl CoA isomerase Prostaglandin-A1 Delta-isomerase 5-carboxymethyl-2-hydroxymuconate D-isomerase Isopiperitenone D-isomerase L-dopachrome isomerase Polyenoic fatty acid isomerase
5.3.4: S-S	Protein disulfide-isomerase (PDIA3)
5.3.99: other	Prostaglandin D2 synthase/Prostaglandin-D synthase Prostaglandin E synthase Prostacyclin synthase Thromboxane-A synthase

v t e Enzymes
Activity	Active site Binding site Catalytic triad Oxyanion hole Enzyme promiscuity Diffusion-limited enzyme Cofactor Enzyme catalysis
Regulation	Allosteric regulation Cooperativity Enzyme inhibitor Enzyme activator
Classification	EC number Enzyme superfamily Enzyme family List of enzymes
Kinetics	Enzyme kinetics Eadie–Hofstee diagram Hanes–Woolf plot Lineweaver–Burk plot Michaelis–Menten kinetics
Types	EC1 Oxidoreductases (list) EC2 Transferases (list) EC3 Hydrolases (list) EC4 Lyases (list) EC5 Isomerases (list) EC6 Ligases (list) EC7 Translocases (list)

Portal:

Biology

Category:

EC 5.3.2