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TTYH3
Identifiers
Aliases	TTYH3, tweety family member 3
External IDs	OMIM: 608919; MGI: 1925589; HomoloGene: 18431; GeneCards: TTYH3; OMA:TTYH3 - orthologs
Gene location (Human) Chr. Chromosome 7 (human) Band 7p22.3 Start 2,631,986 bp End 2,664,802 bp
Gene location (Mouse) Chr. Chromosome 5 (mouse) Band 5|5 G2 Start 140,606,333 bp End 140,634,786 bp
RNA expression pattern Bgee Human Mouse (ortholog) Top expressed in ventricular zone ganglionic eminence stromal cell of endometrium right hemisphere of cerebellum monocyte right frontal lobe mucosa of ileum prefrontal cortex granulocyte cingulate gyrus Top expressed in ventricular zone superior frontal gyrus external carotid artery internal carotid artery primary visual cortex piriform cortex molar genital tubercle hand mesenteric lymph nodes More reference expression data BioGPS n/a
Gene ontology Molecular function chloride channel activity intracellular calcium activated chloride channel activity volume-sensitive chloride channel activity Cellular component integral component of membrane plasma membrane extracellular exosome membrane chloride channel complex Biological process ion transmembrane transport chloride transport ion transport chloride transmembrane transport transport Sources:Amigo / QuickGO
Orthologs Species Human Mouse Entrez 80727 78339 Ensembl ENSG00000136295 ENSMUSG00000036565 UniProt Q9C0H2 Q6P5F7 RefSeq (mRNA) NM_025250 NM_175274 NM_001308039 NM_001308040 RefSeq (protein) NP_079526 NP_001294969 NP_780483 Location (UCSC) Chr 7: 2.63 – 2.66 Mb Chr 5: 140.61 – 140.63 Mb PubMed search
Wikidata
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Tweety family member 3 is a protein that in humans is encoded by the TTYH3 gene.

Function

This gene encodes a member of the tweety family of proteins. Members of this family function as chloride anion channels. The encoded protein functions as a calcium(2+)-activated large conductance chloride(-) channel. .

References

1. ^ GRCh38: Ensembl release 89: ENSG00000136295 – Ensembl, May 2017
2. ^ GRCm38: Ensembl release 89: ENSMUSG00000036565 – Ensembl, May 2017
3. "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
4. "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
5. "Entrez Gene: Tweety family member 3". Retrieved 2020-04-12.

Further reading

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• Genes on human chromosome 7
• Human chromosome 7 gene stubs