Trion may refer to:
- Trion, Georgia, a town in Chattooga County, Georgia, United States
- Trion (neural networks), a localized group of neurons in the cortex and a basic unit in the trion model
- Trion (physics), a quasiparticle in a solid
- Trion Worlds, a video game developer and publisher
- Trion Supercars, an American car manufacturer
In fiction
- Alpha Trion, the name of several fictional characters in the various Transformers universes
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