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Tuomas Knowles is a British scientist and Professor of Physical Chemistry and Biophysics at the Department of Chemistry and at the Cavendish Laboratory at the University of Cambridge. He is the co-director of the Cambridge Centre for Misfolding Diseases and a Fellow of St John's College, Cambridge. Prof. Knowles is a co-founder of four biotechnology companies: Fluidic Analytics, Wren Therapeutics, Xampla and Transition Bio. He was also the Cambridge Enterprise Academic Entrepreneur of the year in 2019.

Education

Tuomas Knowles studied Biology at the University of Geneva and Physics at the Swiss Federal Institute of Technology in Zurich and at the University of Cambridge. He holds a Ph.D. in Physics from the University of Cambridge and a master's degree in Physics from the Swiss Federal Institute of Technology Zurich. He was a visiting scholar at Harvard University and Weston Visiting Professor at the Weizmann Institute of Science in Israel.

Research

The research of Tuomas Knowles focuses on understanding protein behavior in health and disease. Knowles is known for his work on protein aggregation and for describing the kinetics of this process and the underlying molecular mechanisms. He discovered the first integrated rate law for amyloid formation which has allowed the mechanisms of this process to be elucidated by researchers worldwide and together with collaborators he has made software available to the research community for kinetic analysis of protein aggregation. He has published over 300 papers, has an H-index of 70 and has been named Highly Cited Researcher by the Web of Science.

Awards and honors

• Corday-Morgan Prize from the Royal Society of Chemistry (awarded in 2017).
• Raymond and Beverly Sackler International Prize in Biophysics (awarded in 2017).
• Harrison-Meldola Memorial Prize from the Royal Society of Chemistry
• Young Investigator Award and Medal, British Biophysical Society
• Young Scientist Prize in Biological Physics, International Union of Pure and Applied Physics
• Rita and John Cornforth Award, The Royal Society of Chemistry

References

1. "Tuomas Knowles". scholar.google.co.uk.
2. "Tuomas Knowles — Knowles Lab". www-knowles.ch.cam.ac.uk. 9 June 2016.
3. "Professor Tuomas Knowles — Department of Physics". www.phy.cam.ac.uk. 10 May 2019.
4. "Index | Centre for Misfolding Diseases". www.cmd.ch.cam.ac.uk.
5. St John's College, Cambridge
6. "IfM News and Features". www.ifm.eng.cam.ac.uk.
7. "Tuomas Knowles". weitzlab.seas.harvard.edu.
8. Knowles TP, Waudby CA, Devlin GL, Cohen SI, Aguzzi A, Vendruscolo M, et al. (December 2009). "An analytical solution to the kinetics of breakable filament assembly". Science. 326 (5959): 1533–7. Bibcode:2009Sci...326.1533K. doi:10.1126/science.1178250. PMID 20007899. S2CID 6267152.
9. "Five Professors named as 2019 Highly Cited Researchers | Yusuf Hamied Department of Chemistry". www.ch.cam.ac.uk.
10. "Prizes and awards 2017". Royal Society of Chemistry. 9 May 2017.
11. "Past Laureates of the Raymond and Beverly Sackler International Prize in Biophysics". Tel Aviv University. September 5, 2012.
12. "Previous winners". Royal Society of Chemistry.

• Living people
• British scientists
• ETH Zurich alumni
• Alumni of the University of Cambridge
• University of Geneva alumni
• Scientists of the Cavendish Laboratory
• Professors of the University of Cambridge
• Fellows of St John's College, Cambridge