UGL may refer to:
- UGL (company), an Australian engineering company
- UGL Rail, its rolling stock division
- David Adamany Undergraduate Library, at Wayne State University in Detroit, Michigan
- Gellan tetrasaccharide unsaturated glucuronyl hydrolase, an enzyme
- General Labour Union (Italy) (Italian: Unione Generale del Lavoro)
- Underslung grenade launcher
- Union Glacier Blue-Ice Runway, in Antarctica
- Unsaturated chondroitin disaccharide hydrolase, an enzyme
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